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KMID : 0357520190420020137
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Journal of Radiological Science and Technology
2019 Volume.42 No. 2 p.137 ~ p.143
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Dosimetric Comparison of Setup Errors in Intensity Modulated Radiation Therapy with Deep Inspiration Breath Holding in Breast Cancer Radiation Therapy
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Ham Il-Sik
Cho Pyong-Kon
Jung Kang-Kyo
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Abstract
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The aim of this study was analyzed the setup error of breast cancer patients in intensity modulated radiation therapy(IMRT) with deep inspiration breath holding(DIBH) and was analyzed the dose distribution due to setup error. A total of 45 breast cancer cases were performed a retrospective clinical analysis of setup error. In addition, the re-treatment planning was carried by shifting the setup error from the isocenter at the treatment. Based on this, the dose distribution of PTV and OARs was compared and analyzed. The 3D error for small breast group and medium breast group and large breast group were 3.1 mm and 3.7 mm and 4.1 mm, respectively. The difference between the groups was statistically significant(P=0.003). DVH results showed HI, CI for the PTV difference between standard treatment plan and re-treatment plan of 14.4%, 4%. The difference in D5 and V20 of the ipsilateral lung was 5.6%, 13% respectively. The difference in D5 and V5 of the heart of right breast cancer patients was 6.8%, 8% respectively. The difference in D5, V20 of the heart of left breast cancer patients was 7.2%, 23.5% respectively. In this study, there was a significant association between breast size and significant setup error in breast cancer patients with DIBH. In addition, it was found that the dose distribution of the PTV and OARs varied according to the setup error.
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KEYWORD
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Setup error, Deep inspiration breath hold, Intensity modulated radiation therapy, Image guided radiation therapy, Breast cancer
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